Sometime after the creation of Adam and Eve on the sixth day of creation, see Genesis 1:26-31, they rebelled against God by eating the fruit of the tree of the knowledge of good and evil.
“So when the woman saw that the tree was good for food, that it was pleasant to the eyes, and a tree desirable to make one wise, she took of its fruit and ate. She also gave to her husband with her, and he ate.” Genesis 3:6.
“Finally, brethren, pray for us, that the word of the Lord may have free course and be glorified, just as it is with you, and that we may be delivered from unreasonable and wicked men; for not all have faith.” 2 Thessalonians 3:1-2.
The above was covered in the study, Not All Have Faith, 2 Thessalonians 3:1-2, posted on 3-14-21. It is included to maintain context, we will continue here with 2 Thessalonians 3:3 below.
“But the Lord is faithful, who will establish you and guard you from the evil one.” 2 Thessalonians 3:3.
“Finally, brethren, pray for us, that the word of the Lord may have free course and be glorified, just as it is with you, and that we may be delivered from unreasonable and wicked men; for not all have faith.” 2 Thessalonians 3:1-2.