“In this the love of God was manifested toward us, that God has sent His only begotten Son into the world, that we might live through Him. In this is love, not that we loved God, but that He loved us and sent His Son to be the propitiation for our sins.” 1 John 4:9-10.
Sometime after the creation of Adam and Eve on the sixth day of creation, see Genesis 1:26-31, they rebelled against God by eating the fruit of the tree of the knowledge of good and evil.
“So when the woman saw that the tree was good for food, that it was pleasant to the eyes, and a tree desirable to make one wise, she took of its fruit and ate. She also gave to her husband with her, and he ate.” Genesis 3:6.
“When Pilate saw that he could not prevail at all, but rather that a tumult was rising, he took water and washed is hands before the multitude, saying, ‘I am innocent of the blood of this just Person. You see to it.’ And all the people answered and said, ‘His blood be on us and on our children.’” Matthew 27:24-25.