Sometime after the creation of Adam and Eve on the sixth day of creation, see Genesis 1:26-31, they rebelled against God by eating the fruit of the tree of the knowledge of good and evil.
“So when the woman saw that the tree was good for food, that it was pleasant to the eyes, and a tree desirable to make one wise, she took of its fruit and ate. She also gave to her husband with her, and he ate.” Genesis 3:6.
“…He who now restrains will do so until He is taken out of the way. And then the lawless one will be revealed, whom the Lord will consume with the breath of His mouth and destroy with the brightness of His coming.” 2 Thessalonians 2:7b-8.
“The coming of the lawless one [Antichrist, man of sin] is according to the working of Satan, with all power, signs, and lying wonders…” 2 Thessalonians 2:9.
“Therefore be patient, brethren, until the coming of the Lord. See how the farmer waits for the precious fruit of the earth, waiting patiently for it until it receives the early and latter rain. You also be patient. Establish your hearts, for the coming of the Lord is at hand.” James 5:7-8.
“Do not grumble against one another, brethren, lest you be condemned. Behold, the Judge is standing at the door!” James 5:9.
“Blessed is the man who endures temptation; for when he has been proved, he will receive the crown of life which the Lord has promised to those who love Him.” James 1:12.