Sometime after the creation of Adam and Eve on the sixth day of creation, see Genesis 1:26-31, they rebelled against God by eating the fruit of the tree of the knowledge of good and evil.
“So when the woman saw that the tree was good for food, that it was pleasant to the eyes, and a tree desirable to make one wise, she took of its fruit and ate. She also gave to her husband with her, and he ate.” Genesis 3:6.
“…He who now restrains will do so until He is taken out of the way. And then the lawless one will be revealed, whom the Lord will consume with the breath of His mouth and destroy with the brightness of His coming.” 2 Thessalonians 2:7b-8.
“And now you know what is restraining, that he [Antichrist] may be revealed in his own time. For the mystery of lawlessness is already at work; only He who now restrains will do so until He is taken out of the way.” 2 Thessalonians 2:6-7.
